Publications

Original Articles

Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, and Khazaie K.

Direct presentation of antigen protects against CD8 T-cell mediated intestinal autoimmunity.

Gastroenterol. 2008. 134(4):1028-37. PDF

Epardaud M, Rubinstein MP, Yonekura A, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath AW, Turley SJ.

IL-15/IL-15Ralpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.

Can Res. 2008. 68(8):2972-83. PDF

Lee JW, Epardaud M, Sun J, Becker JE, Cheng AC, Yonekura A, Heath JK, Turley SJ.

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.

Nat Immunol. 2007. 8;2: 181-190. PDF

Turley SJ, Lee JW, Dutton-Swain N, Mathis D. Benoist C.
Endocrine self and gut non-self intersect in pancreatic lymph nodes.
PNAS 2005 e-published November 29 PDF

Lee LF, Xu B, Michie S, Turley S, McDevitt HO.
The role of TNFa in the pathogenesis of type-1 diabetes in the NOD mouse: Analysis of dendritic cell maturation.
PNAS 2005 102:15995-16000 PDF

Turley S, Poirot L, Hattori M, Benoist C, Mathis D.
Physiological b-cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model.
J Exp Med. 2003.198:1527-37. Pubmed

Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins S, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D.
Projection of an immunological self-shadow within the thymus by the aire protein.
Science 2002. 298:1395-401. Pubmed

Yang J-M, Baserga SJ, Turley SJ, Pollard KM. 
Fibrillarin and other snoRNP proteins are targets of autoantibodies in xenobiotic-induced autoimmunity. 
Clin. Immunol. 2001. 101:38-50. Pubmed

Garrett WS, Chen LM, Kroscheswski R, Ebersold M, Turley S,Trombetta S, Galan JE, Mellman I.
Developmental control of endocytosis in dendritic cells by Cdc42.
Cell. 2000.102:325-334. Pubmed

Inaba K, Turley SJ, Iyoda T, Yamaide F, Shimoyama S, Reis e Sousa C, Germain R. Mellman I, Steinman RM.
The formation of immunogenic MHC class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. 
J. Exp. Med. 2000. 191:927-936.  Pubmed

Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaerher J, Steinman RM, Mellman I. 
Transport of peptide-MHC class II complexes in developing dendritic cells.
Science. 2000.  288:522-527. Pubmed

Talmor M, Mirza A, Turley S, Mellman I, Hoffman LA, Steinman RM.
Generation of large numbers of immature and mature dendritic cells from rat bone marrow cultures. 
Eur. J. Immunol. 1998. 28:811-817. Pubmed

Inaba K, Turley SJ, Yamaide F, Iyoda T, Pack M, Inaba M,. Mahnke K, Sauter B, Albert M, Subklewe M, Sheff D, Bhardwaj, N, Mellman I, Steinman RM.   
Efficient presentation of phagocytosed cellular fragments on MHC class II products of dendritic cells.  
J. Exp. Med. 1998. 188:2163-2173. Pubmed

Turley SJ*, Pierre P*, Gatti E, Hull M, Meltzer J, Mirza A, Inaba K, Steinman RM, Mellman I. *coauthors. 
Developmental regulation of MHC class II transport in mouse dendritic cells.
Nature. 1997.  388:787-79 Pubmed

Sacca R, Turley S, Soong L, Mellman I, Ruddle N.  
Transgenic expression of lymphotoxin restores lymph nodes to lymphotoxin-a-deficient mice.
J. Immunol. 1997.159:4252-4260. Pubmed

Pierre P, Turley SJ, Meltzer J, Mirze A, Steinman R, Mellman I.
Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells.
Adv. Exp. Med. Biol. 1997. 417:179-182. 

Hultman P, Turley SJ, Enestrom S, Lindh U, Pollard KM.
Murine genotype influences the specificity, magnitude, and persistence of murine mercury-induced autoimmunity.
J. Autoimmun. 1996. 9:139-149. Pubmed

Takeuchi K, Turley SJ, Tan EM, Pollard KM.   
Analysis of the autoantibody resonse to fibrillarin in human disease and murine models of autoimmunity. 
J. Immunol. 1995. 154:961-971. Pubmed

Hultman P, Ganowiak K, Turley SJ, Pollard KM.
Genetic susceptibility to silver-induced anti-fibrillarin autoantibodies in mice. 
Clin. Immunol. Immunopathol.  1995. 77:291-297. Pubmed

Hultman P, Johansson U, Turley SJ, Lindh U, Enestrom S, Pollard KM. 
Adverse immunological effects and autoimmunity induced by dental amalgam and alloy in mice.
FASEB. J. 1994. 8:1183-1190. Pubmed

Hultman P, Enestrom S, Turley SJ, Pollard KM. 
Selective induction of anti-fibrillarin autoantibodies by silver nitrate in mice. 
Clin. Exp. Immunol. 1994. 96:285-291. Pubmed

Turley SJ, Tan EM, Pollard KM.   
Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin. 
Biochim. Biophys. Acta. 1993. 1216:119-122. Pubmed

Reviews, Chapters, and Editorials

Collier AY, Lee JW, and Turley SJ. 
“Self-encounters of the third kind: Lymph node stroma in CD8+ T cell tolerance.”
Muc. Immunol. Advance online publication, May 14, 2008; doi:10.1038/mi.2008.19.

Reynoso E, Lee JW, and Turley SJ.
“The role of lymph node stromal cells in peripheral tolerance”
In Crossroads between Innate and Adaptive Immunity Volume II, editors S. Schoenberger, B. Pulendran, 2008.

Romani N, Turley S, Pypaert M, Ebersold M, Mellman I, Schuler G, Steinman R. 
“Dendritic cells”
in Atlas of Blood Cells: Function and Pathology, 2003. 

D. Zucker-Franklin and C.E. Grossi (Eds.) pp. 449-478. Turley SJ. 
Dendritic cells: inciting and inhibiting autoimmunity. 
Curr. Opin.Immunol.  2002.  14:765-770. Pubmed

Steinman RM, Turley S, Mellman I, Inaba K.
The induction of tolerance by dendritic cells that have captured apoptotic cells.
J. Exp. Med. 2000. 191:411-416. Pubmed

Steinman RM, Inaba K, Turley SJ, Pierre P, Mellman I.  
Antigen capture, processing,and presentation by dendritic cells: recent cell biological studies.
Human Immunol. 1999. 60:562-567. Pubmed

Albert ML, Turley S, Garrett W, Mellman I, Inaba K, Bhardwaj N, Steinman RM.
"Uptake and presentation of phagocytosed antigens by dendritic cells".
In Phagocytosis: The Host; Advances in Cell and Molecular Biology of Membranes and Organelles, 1999.

S. Gordon and A. Tartakoff (Eds.) pp. 363-378.Turley SJ, Steinman RM, Mellman I, Inaba K.   
"Propagation and culture of dendritic cells".
In Dendritic Cells: Biology and Clinical Applications, 1999. Academic Press, editors M Lotze, Thomson A, pp. 535-553.

Mellman, I, Turley SJ, Steinman RM.
Antigen processing for amateurs and professionals. 
Trends Cell Biol. 1998. 8:231-237. Pubmed

In the Press

Tuma, RS.

How the body Protect the Gut

Discover, e-published January 11, 2008.

Morton, CC.

Lymph Node Cells Mimic Thymus to Induce Immune Tolerance

Focus Online, New from Harvard Medical, Dental, and Public Health Studies- e-published January 26, 2007.

Cromie, WJ.

Saving Your Self from Yourself: Separating Good Gut Bacteria from the Bad.

Harvard University Gazette, e-published February 8, 2007.