Ting-Xi Liu, M.D., Ph.D.

Affiliation: DFCI
Position: Post Doctoral Fellow
Address: 44 Binney Street, Boston MA 02115, Mayer 630
Email: tingxi_liu@dfci.harvard.edu
Phone: (617) 632-5826

Education/Training:

1990, B.S. Department of Medicine, Gui Yang Medical College, Gui Zhou Province

1996, M.D. Institute of Hematology, Union Hospital, Tong Ji Medical University, Wu Han, Hu Bei Province

1999, Ph.D. Shang Hai Institute of Hematology, Key Laboratory for Human Genome Research, Rui Jin Hospital, Shang Hai Second Medical University, Shang Hai, China

1990-93, Resident, Department of Internal Medicine, Hospital affiliated with Gui Yang Medical College

1994-96, Resident Department of Hematology, Union Hospital, Tong Ji Medical University, Wu Han, Hu Bei Province

1999-present, Fellow in Pediatric Oncology, Dana-Farber Cancer Institute, Boston MA

Publications:

1. Liu TX, Liu XF, Xiang JP. Study on the relationship between the expression of adhesion molecules and the invasiveness of acute myeloid leukemia cells. Chinese J of Hematol 18:29-30, 1997.
2. Liu TX, Liu XF, Zhou P. Study on the expression of adhesion molecules VLA-4, LFA-1 in acute myeloid leukemia: the feature of expression and its clinical implications. Clin J of Hematol 10:152-4, 1997.
3. Liu TX, Liu XF. The development of hematopoietic progenitor cells and cytoadhesions. Clinical J of Hematol 10:79-81, 1997.
4. Liu TX, Mao M, Chen Z, Wang ZY. Acute promyelocytic leukemia: Progress in the pathogenesis and mechanism of induced differentiation. Chinese J of Hematol 19:29-30, 1999.
5. Liu TX, Zhang JW, Tao J, Zhang RB, Zhang QH, Zhao CJ, Tong JH, Lanotte M, Waxman S, Chen SJ, Mao M, Hu GX, Zhu L, Chen Z. Gene expression networks underlying retinoic acid-induced differentiation of acute promyelocytic leukemia cells. Blood. 2000, 96(4):1496-504.
6. Bennett CM, Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the zebrafish, Danio rerio. Blood. 2001, 98(3):643-51.

Abstract and Posters:

1. Liu TX, Zhang JW, Zhang RB et al. Identification of the molecular pathways underlying the retinoic acid-induced differentiation of acute promyelocytic leukemia cells. American Society of Hematology Fortieth Annual Meeting(abstract). 4-8, Dec, 1998 Miami Beach, Abstract#784, Page 193a
2. Liu TX, Zhou Y, Kanki JP, Zon LI, Look AT. Identification of chromosomal regions in the zebrafish syntenic with human 5q- syndrome. Zebrafish Development&Genetics(abstract). 26-30, April, 2000 Cold Spring Harbor, Abstract#186, Page 186.
3. Rhodes J, Bennett CM, Kanki JP, Liu TX, Paw BH, Zon LI, Look AT. Molecular analysis of zebrafish myelopoiesis. American Society of Hematology Forty-second Annual Meeting(abstract). 1-5, Dec, 2000 Moscone Center, Abstract#3483, Page 806a
4. Preliminary study on the role of the cAMP-PKA pathway during retinoic acid-induced APL cell differentiation. Tao J, Zhao Q, Zhang JW, Liu TX, Zhang QH, Chen SJ, Chen Z. American Society of Hematology Forty-second Annual Meeting(abstract). 1-5, Dec, 2000 Moscone Center, Abstract#1288, Page 299a
5. Liu TX, Zhou Y, Kanki JP, Zon LI, Look AT. Syntenic region shared by zebrafish and patients with 5q- syndrome. American Society of Hematology Forty-second Annual Meeting(abstract). 1-5, Dec, 2000 Moscone Center, Abstract#380, Page 89a
6. Bennett CM, Fleming MD, Kanki JP, Rhodes J, Delahaye-Brown A, Langenau DM, Liu TX, Paw BH, Zon LI, Look AT. Genetic analysis of myelopoiesis in the zebrafish. American Society of Hematology Forty-second Annual Meeting(abstract). 1-5, Dec, 2000 Moscone Center, Abstract#4177, Page 114b
7. Zhang JW, Zhu HQ, Niu C, Tao J, Liu TX, Zhao CJ, Zhang QH, Yu Y, Jia PM, Wang HH, Mao M, Wang ZY, Tong JH, Waxman S, Chen SJ, Chen Z. Functional study on several novel retinoic acid induced genes(RIGs). American Society of Hematology Forty-second Annual Meeting(abstract). 1-5, Dec, 2000 Moscone Center, Abstract#4281, Page 136b

Awards and Honors::

1. 1999: First-class, Clyde Wu Foundation
2. 1999: First-class, Federal Pharmaceutical Award

Research Interests :

1. The relationship between integrin adhesion molecules and acute myelocytic leukemia.
2. The molecular mechanism of induction differentiation underlying the retinoic acid-induction of acute promyelocytic leukemia.
3. The pathogenesis of acute myelocytic leukemia using zebrafish as an in vivo model.