Krop I, Marz A, Carlsson H, Li X, Bloushtain-Qimron N, Hu M, Gelman R, Sabel MS, Schnitt S, Ramaswamy S, Kleer CG, Enerback C, Polyak K. A putative role for psoriasin in breast tumor progression. Cancer Res 2005; 65:11326-11334. Download pdf (1.9MB)

Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K. HIN-1, an inhibitor of cell growth, invasion, and AKT activation. Cancer Res 2005; 65:9659-9669. Download pdf (1.6MB)

Hu M, Yao J, Cai L, Bachman KE, van den Brule F, Velculescu V, Polyak K. Distinct epigenetic changes in the stromal cells of breast cancers. Nature Genet 2005; Download pdf (1MB)

Allinen M, Beroukhim R, Cai L, Brennan C, Lahti-Domenici J, Huang H, Porter D, Hu M, Chin L, Richardson A, Schnitt S, Sellers WR, Polyak K. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell. 2004 Jul;6(1):17-32. [ Download pdf (2450 KB) | Download 27 SAGE libraries analyzed in this paper (raw data)]

Krop I, Player A, Tablante A, Taylor-Parker M, Lahti-Domenici J, Fukuoka J, Batra SK, Papadopoulos N, Richards WG, Sugarbaker DJ, Wright RL, Shim J, Stamey TA, Sellers WR, Loda M, Meyerson M, Jen J, Polyak K. Frequent HIN-1 promoter methylation and loss of expression in multiple human tumor types. Mol Can Res 2004; 2: 489-494. Download pdf (1.4MB)

Porter D, Weremowicz S, Koei Chin, Seth P, Keshaviah A, Lahti-Domenici J, Bae YK, Monitto CL, Merlos-Suarez A, Chan J, Hulette CM, Richardson A, Morton CC, Marks J, Duyao M, Hruban R, Gabrielson E, Gelman R, and Polyak K. A neural growth factor is a candidate oncogene in breast cancer. Proc Natl Acad Sci. 2003; 100:10931-10936. Download pdf (640 KB)

Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K. Lack of HIN-1 methylation in BRCA1 linked and “BRCA1-like” breast tumors. Cancer Res. 2003; 63:. Download pdf (172 KB)

Porter D, Lahti-Domenici J, Keshaviah A, Bae YK, Argani P, Marks J, Richardson A, Cooper A, Strausberg R, Riggins GJ, Schnitt S, Gabrielson E, Gelman R, Polyak K. Molecular markers in ductal carcinoma in situ of the breast. Mol Cancer Res. 2003; 1:362-375. Download pdf (308 KB)

Porter DA, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K. Expression of HIN-1 and UGRP-1 in adult and developing tissues. Mech Dev 2002; 114:201-204. Download pdf (335 KB)

Seth P, Krop IE, Porter DA and Polyak K. Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression). Oncogene 2002; 21:836-843. Download pdf (508 KB)

Enerbäck C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, and Polyak K. Psoriasin Expression in Mammary Epithelial Cells in Vitro and in Vivo. Cancer Res 2002; 62: 43–47. Download pdf (320 KB)

Polyak K. On the birth of breast cancer. Biochem Biophys Acta. 2001; 1552:1-13. Download pdf (737 KB)

Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, and Polyak K. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proc Natl Acad Sci 2001; 98:9796-9801. Download pdf (351 KB)

Porter DA, Krop IE, Nasser S, Sgroi D, Kaelin CM, Marks JR, Riggins G, and Polyak K. A SAGE (Serial Analysis of Gene Expression) view of breast tumor progression. Cancer Res 2001; 61:5697-5702. Download pdf (278 KB)

Polyak K and Riggins G. Gene Discovery using the SAGE technique: Implications for Cancer Research. J Clinic Onc 2001; 19:2948-2958. Download pdf (1,598 KB)

Seth P, Lunetta KL, Bell DW, Gray H, Nasser SM, Rhei E, Kaelin CM, Iglehart DJ, Marks J, Garber JE, Haber DA and Polyak K. Phenol sulfotransferases: hormonal regulation, polymorphism and age of onset of breast cancer. Cancer Res 2000;60:6859-6863. Download pdf (93 KB)

Seth P, Porter D Lahti-Domenici J, Geng Y, Richardson A, and Polyak K. Cellular and molecular targets of estrogen in normal human breast tissue. Cancer Res. 2002; 62:4540-4544. Download pdf (256 KB)

Polyak K. Molecular alterations in ductal carcinoma in situ of the breast. Curr Opin Onc. 2002; 14:92-96. Download pdf (135 KB)

Polyak K. Breast cancer gene discovery. Exp. Rev. Mol. Med. 2002; August 15. www.expertreviews.org/0200491Xh.htm