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Manuscript pdf file

News and Views

Bcl2 genotyping protocol

DNA extraction protocol from ear punch

RNA isolation protocol

Download Expression Data from GEO accession number GSE1413

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

J. Guillermo Paez*, Pasi A. Jänne,*, Jeffrey C. Lee,*, Sean Tracy, Heidi Greulich, Stacey Gabriel, Paula Herman, Frederic J. Kaye, Neal Lindeman, Titus J. Boggon, Katsuhiko Naoki,
Hidefumi Sasaki, Yoshitaka Fujii, Michael J. Eck,
William R. Sellers#, Bruce E. Johnson#, Matthew Meyerson#

* co-first authors

# co-corresponding authors

Science 2004 (in press)

Download Manuscript pdf file Table S2 EGFR mutations Table S3 EGFR mutations/Iressa response Chromatograms Nat Med News and Views Cancer Cell Review

A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens

Andrew C. Hsieh, Ronghai Bo, Judith Manola, Francisca Vazquez, Olivia Bare, Anastasia Khvorova, Stephen Scaringe and William R. Sellers

Nucleic Acids Research 2004; 32, 893-901

Download Manuscript pdf file Supplemental Table I Supplemental Table II Supplemental Table III Knockdown data linked to gene and siRNA oligo information (excel format)

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transciption factor in PTEN-deficient tumor cells

Tweeny R. Kau, Frank Schroeder, Shivapryia Ramaswamy, Cheryl L. Wojciechowski, Jean J. Zhao, Thomas M. Roberts, Jon Clardy, William R. Sellers and Pamela A. SIlver

Cancer Cell 2003; 4, 463-476pdf

Download Manuscript pdf file Mini-review Mini-review Wang and El-Deiry

Genome-wide loss-of-heterozygosity analysis from laser-capture microdissected prostate cancer using SNP arrays and a novel bioinformatics platform dChipSNP

Marshal E. Lieberfarb*, Ming Lin*, Mirna Lechpammer, Cheng Li, David M. Tanenbaum, Philip Febbo, Rene Wright, Judy Shim, Philip W. Kantoff, Massimo Loda, Matthew Meyerson and William R. Sellers

*contributed equally

Cancer Res 2003; 63, 4781-4785 pdf

Supporting Material Supp. Figure 1A Supp. Figure 1B Supp. Figure 1C Supp. Figure 1D Supp. Figure 1E Supp. Figure 1F Supp. Figure 1 Legend Supplemental Table I Summary LOH Data

Raw Data Files (in progress) Links for dCHIP http://www.dchip.org/ dCHIP lab page

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation – the MPAKT model

Pradip K. Majumder*, Jen Jen Yeh*, Daniel J. George, Phillip G. Febbo, Jennifer Kum, Xi Que, Rachel Bikoff, Hongfeng Ma, Philip W. Kantoff, Todd R. Golub, Massimo Loda, William R. Sellers

Now Available from the MMHC Repository click here

*contributed equally

PNAS 2003; 100:7841-7846 pdf

Supporting Material Supporting Figure 6 : Legend Supporting Figure 7 : Legend Supporting Figure 8 : Legend Supporting Table 1 Supporting Table 2 Supporting Table 3 Supporting Table 4 Raw Data (CEL) Files 1 2 3 4 5 6 7 8 Other Data Files Genes Ranked by the Signal-to-Noise Metric

Supplemental Methods MPAKT genotyping protocol Tissue dissection and processing Tail DNA extraction protocol

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR

Shivapriya Ramaswamy*, Noriaki Nakamura*, Isabelle Sansal, Louise Bergeron, William R. Sellers

*contributed equally

Cancer Cell 2002, 2(1): 81-91 pdf

Supplemental Information Supplemental Information Supplemental Figure 1 Supplemental Figure 2

Experimental Data Experiment 1 download data Experiment 2 download data Experiment 3 download data